Clinical Trials Directory

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UnknownNCT02998853

Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure

Reliability of 3D Angio QFR Evaluation of Non Culprit Stenoses in STEMI Patients During First Acute Interventional Procedure: Comparison With Staged Procedure FFR

Status
Unknown
Phase
Study type
Observational
Enrollment
120 (estimated)
Sponsor
Azienda Ospedaliera Sant'Anna e San Sebastiano · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

Reliability of 3D angio QFR functional evaluation of all non culprit lesions \>50% in STEMI patients during first acute procedure

Detailed description

3DAngio QFR is an angiographic based tool for coronary stenosis functional assessment: it is validated versus Adenosine FFR(ADOFFR) by several studies (FAVOR, VIRTU-1) ; in particular post contrast QFR (cQFR) showed a very good correlation with ADOFFR. Furthermore ADOFFR in non culprit vessel in acute stage of STEMI correlates well with ADOFFR of the same non culprit lesion in staged procedure. Aim of the study is to find a valid correlation between cQFR in acute study and ADOFFR in the staged procedure. A positive result may lead to a fast, easy and cost effective acute functional non culprit lesions evaluation during acute procedure for STEMI patients, selecting those,if any, to be treated immediately or in a staged procedure.

Conditions

Interventions

TypeNameDescription
OTHERQFR measurement by dedicated workstation on xrays angio selected runsThe patient undergoes coronary angiography; if at least one stenosis from 40 to 90% in non culprit is present and FFR is indicated by guidelines the patient is enrolled to 3d Angio QFR evaluation; no adjunctive invasive procedures are needed for QFR measurements

Timeline

Start date
2016-11-01
Primary completion
2017-11-01
Completion
2017-12-01
First posted
2016-12-21
Last updated
2016-12-21

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT02998853. Inclusion in this directory is not an endorsement.