NCT02996916

Efficacy of Olmesartan on Cerebral Glucose Metabolism, Vascular Inflammation and Adipose Tissue

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Kurume University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Hypertension is a leading risk factor for morbidity and mortality worldwide. The brain is a major target of the damaging effects of hypertension. Hypertension has been recognized as the leading cause of dementia as well as the most important risk factor for stroke and vascular cognitive impairment. Although glucose is the principal cerebral energy source, impact of hypertensive treatment on cerebral glucose metabolism is poorly understood.

Conditions

• Efficacy of Olmesartan on Cerebral Glucose Metabolism in Essential Hypertension

Interventions

Type	Name	Description
DRUG	Olmesartan	10-40mg daily
DRUG	Amlodipine	2.5-10mg daily

Timeline

• Start date: 2015-12-01
• Primary completion: 2018-12-01
• Completion: 2020-12-01
• First posted: 2016-12-19
• Last updated: 2016-12-20

Locations

1 site across 1 country: Japan