NCT02995772

Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients

Preoperative Neoadjuvant Hormonal Therapy and Neoadjuvant Chemotherapy for Stage IIIB and IV Breast Cancer Patients in Dharmais National Cancer Center Hospital, Indonesia

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 122 (actual)
• Sponsor: Dharmais National Cancer Center Hospital · Other Government
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This study compared long term outcome of stage IIIB/C and IV breast cancer patients treated with neoadjuvant hormonal therapy (NAHT) and those treated with neoadjuvant chemotherapy (NACT)

Detailed description

This study compared long term outcome of stage IIIB/C and IV breast cancer patients treated with neoadjuvant hormonal therapy (NAHT) and those treated with neoadjuvant chemotherapy (NACT) between 2011 and 2016. The primary end points are overall survival (OS) and progression free survival (PFS) with Kaplan Meier. This study was approved by Ethical Committee in Dharmais National Cancer Hospital.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	Aromatase Inhibitors (Arimidex)	Comparison of efficacy with chemotherapy
DRUG	Tamoxifen	Comparison of efficacy with chemotherapy
PROCEDURE	SOB	Comparison of efficacy with chemotherapy
DRUG	FAC	Comparison of efficacy with hormonal therapy
DRUG	Aromatase Inhibitors (Femara)	Comparison of efficacy with chemotherapy
DRUG	Aromatase Inhibitors (Aromasin)	Comparison of efficacy with chemotherapy

Timeline

• Start date: 2011-11-01
• Primary completion: 2018-11-01
• Completion: 2018-11-01
• First posted: 2016-12-16
• Last updated: 2019-06-19

Locations

1 site across 1 country: Indonesia