Clinical Trials Directory

Trials / Completed

CompletedNCT02993705

Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)

Phase II Trial On Trabectedin In The Treatment Of Advanced Uterine And Ovarian Carcinosarcoma (CS)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
45 (actual)
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
Sex
Female
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

Multicenter phase II study on trabectedin in patients advanced uterine and ovarian carcinosarcoma. Patients will receive trabectedin until disease progression or unacceptable toxicity. Disease response evaluation will be assessed every 9 weeks.

Detailed description

This is a Phase II, multi-centre, single arm study aiming at evaluating efficacy and toxicity of Trabectedin in a population of advanced or recurrent ovarian and uterine carcinosarcoma. Trabectedin will be infused at the dose of 1.3 mg/m2 as a 3- hour iv infusion every 3 weeks via a central venous catheter.

Conditions

Interventions

TypeNameDescription
DRUGTrabectedinChemotherapy drug

Timeline

Start date
2017-02-22
Primary completion
2019-11-13
Completion
2019-11-13
First posted
2016-12-15
Last updated
2021-08-25

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT02993705. Inclusion in this directory is not an endorsement.