NCT02991677

Exercise Effect on Chemotherapy-Induced Neuropathic Pain

Exercise Effect on Chemotherapy-Induced Neuropathic Pain, Peripheral Nerve Fibers

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Baltimore VA Medical Center · Federal
• Sex: All
• Age: 21 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Chemotherapy-induced peripheral neuropathy (CIPN) continues to be a serious healthcare concern. It is painful, persistent, resistant to conventional pain therapies, and results in long-term suffering and decreased quality of life for many cancer survivors. The role of exercise to decrease CIPN-related neuropathic pain (CIPN-NP) will be investigated, with the goal of identifying the mechanisms associated with this therapeutic approach to manage CIPN-NP.

Conditions

• Cancer, Breast
• Cancer, Colorectal
• Cancer, Lung
• Cancer, Ovarian

Interventions

Type	Name	Description
BEHAVIORAL	aerobic exercise intervention	Exercise physiologist supervised walking or running on the treadmill 3 times weekly for 12 weeks.
OTHER	control group	weekly contact by study staff with survivorship information offered not related to neuropathy.
BEHAVIORAL	resistive training	Exercise physiologist supervised upper and lower extremity resistive training 3 times weekly for 12 weeks

Timeline

• Start date: 2018-03-01
• Primary completion: 2025-06-01
• Completion: 2025-12-01
• First posted: 2016-12-13
• Last updated: 2024-08-06

Locations

1 site across 1 country: United States