NCT02984696

Total Antioxidant Capacity Before and After HRT in Hypotalamic Amenorrhea

Effects of 6 Months of HRT on Total Antioxidant Capacity in Patients Affected by Hypotalamic Amenorrhea

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Catholic University of the Sacred Heart · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The aim of our study is to investigate the effects of 6 months oh HRT on total anti-oxidant capacity, clinical, endocrine and metabolic features in women affected by hypotalamic amenorrhea. The study group included 20 patients treated with 1 mg of transdermal estradiol daily and 10mg of oral Medroxyprogesterone acetate from 16th to 24th day of therapy for six months. Menstrual pattern, anthropometric parameters, hormonal assays, DXA and bone metabolism parameters are evaluated before and after therapy.

Conditions

• Hypothalamic Amenorrhea

Interventions

Type	Name	Description
DRUG	1 mg of transdermal estradiol daily and 10mg of oral MPA

Timeline

• Start date: 2015-03-01
• Primary completion: 2016-10-01
• Completion: 2017-12-01
• First posted: 2016-12-07
• Last updated: 2016-12-07

Locations

1 site across 1 country: Italy