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Active Not RecruitingNCT02984566

Liver Ablative Radiotherapy Utilising Kilovoltage Intrafraction Monitoring (KIM)

LARK: Liver Ablative Radiotherapy Utilising Kilovoltage Intrafraction Monitoring (KIM)

Status
Active Not Recruiting
Phase
N/A
Study type
Interventional
Enrollment
32 (actual)
Sponsor
University of Sydney · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

Primary and secondary liver cancer patients will receive liver SABR with or without KIM intervention.

Detailed description

This is a single arm, phase II, two stage study designed to evaluate cancer targeting accuracy, treatment outcomes and treatment efficiency in 46 patients eligible for SABR for either primary or secondary liver malignancy with the incorporation of KIM.

Conditions

Interventions

TypeNameDescription
DEVICEKilovoltage Intrafraction MonitoringKIM is a novel intrafraction real-time tumour localization method. It involves a single gantry-mounted kV x-ray imager acquiring 2D projections of implanted fiducial markers. 3D positions are then reconstructed by maximum likelihood estimation of a 3D probability density function.

Timeline

Start date
2020-01-14
Primary completion
2026-01-01
Completion
2026-01-01
First posted
2016-12-07
Last updated
2025-04-04

Locations

4 sites across 1 country: Australia

Source: ClinicalTrials.gov record NCT02984566. Inclusion in this directory is not an endorsement.