Clinical Trials Directory

Trials / Completed

CompletedNCT02984514

Brown Adipose Tissue in Type 1 Diabetes

Studies of Activity of Brown Adipose Tissue With Positron Emission Tomography Using the Tracer 18F-deoxy Glucose in Patients With Type 1 Diabetes

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
11 (actual)
Sponsor
Per-Ola Carlsson · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Brown adipose tissue has the capacity to consume large amounts of energy and has insulin-independent glucose uptake. The investigators have recently observed an inverse correlation between irisin levels and insulin needs of type 1 diabetes patients. Transplantation of brown adipose tissue to insulin-deficient rats normalized their blood glucose levels. In this study 12 patients with long-standing type 1 diabetes (\>10 years) and with variable exogenous insulin needs will be investigated for amount of brown adipose tissue with positron emission tomography using the tracer 18F-deoxy glucose.

Conditions

Interventions

TypeNameDescription
RADIATIONPositron emission tomography with tracer 18F-deoxy glucoseAssessment of activity of brown adipose tissue with positron emission tomography using the tracer 18F-deoxy glucose

Timeline

Start date
2015-10-01
Primary completion
2018-01-01
Completion
2018-06-01
First posted
2016-12-07
Last updated
2018-10-11

Locations

1 site across 1 country: Sweden

Source: ClinicalTrials.gov record NCT02984514. Inclusion in this directory is not an endorsement.