NCT02984280

Specific Respiratory Infections as Triggers of Acute Medical Events

Specific Respiratory Infections as Triggers of Acute Medical Events: Time Series Analysis Using LabBase and Hospital Episode Statistics

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 787,000 (actual)
• Sponsor: University College, London · Academic / Other
• Sex: All
• Age: 45 Years
• Healthy volunteers: Not accepted

Summary

This study will investigate whether there is a population-level association between circulating respiratory viruses and NHS hospital admissions for acute vascular events using data from national infection surveillance and Hospital Episode Statistics.

Detailed description

We will conduct a time series study correlating anonymised population level data on all samples from NHS laboratories testing positive for six common respiratory viruses with admissions to NHS hospitals in England for a range of cardiac and vascular outcomes over the time period 01/01/2004 to 31/12/2014. This will involve generating Poisson regression models controlling for factors such as seasonal and long-term trends, environmental temperature and humidity. This study is funded by an Academy of Medical Sciences Starter Grant for Clinical Lecturers.

Conditions

• Influenza, Human
• Respiratory Syncytial Virus Infections
• Parainfluenza
• Rhinovirus
• Adenovirus
• Human Metapneumovirus Pneumonia
• Cardiovascular Diseases

Timeline

• Start date: 2016-09-01
• Primary completion: 2017-03-01
• Completion: 2017-03-01
• First posted: 2016-12-06
• Last updated: 2017-05-04

Locations

1 site across 1 country: United Kingdom