Trials / Completed
CompletedNCT02982057
Non Culprit Lesion Study
A Randomized Trial of the Treatment of Non- Culprit Lesion After STEMI: Bioresorbable Vascular Scaffold Versus Optimal Medical Therapy (NCLstudy)
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 50 (actual)
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the present study is to compare the evolution of non culprit lesions after treatment by BVS versus optimal medical therapy at 2-years follow- up
Detailed description
Objectives and hypothesis: scaffolding a non culprit /vulnerable coronary plaque with BVS could facilitate the stabilization process into the atherosclerotic plaque with modifications of plaque morphology, especially the lipid content which is considered as one of the main factor leading to recurrent MACE after an ACS. The interaction between the polymer Platform and the vessel wall, the effect of the everolimus on neointima growth and cellular response into the media could reduce the inflammatory process into the vulnerable plaque could be different Under OMT and BVS implantation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | the ABSORB:bioresorbable vascular scaffold | |
| DRUG | O.M.T |
Timeline
- Start date
- 2015-01-01
- Primary completion
- 2019-11-01
- Completion
- 2019-11-01
- First posted
- 2016-12-05
- Last updated
- 2020-05-05
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT02982057. Inclusion in this directory is not an endorsement.