NCT02979210

Infant Fecal Insult Study

Fecal Insult Study: An Exploratory Study to Evaluate the Microbial Consortia and Skin Barrier Function After Exposure to Artificial Fecal Irritants

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Kimberly-Clark Corporation · Industry
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The rationale for the study is to better understand the dynamics of skin microflora following skin barrier disruption in an adult dermatitis model. The results from this study will provide insights in the complex interaction between skin microbiome and epidermis under normal and disease conditions

Conditions

• Dermatitis

Interventions

Type	Name	Description
OTHER	Artificial Fecal Insult	protease/bile acid cocktail 200 microliters (1500 µg/ml trypsin/chymotrypsin protease mixture, 6.5 mg/ml cholic acid sodium, 6.2 mg/ml deoxycholic acid sodium, and 3.1 mg/ml chenodeoxycholic acid sodium in phosphate buffered saline
OTHER	Phosphate Buffered Saline	200 microliters of phosphate buffered saline

Timeline

• Start date: 2016-11-01
• Primary completion: 2017-01-26
• Completion: 2017-02-01
• First posted: 2016-12-01
• Last updated: 2017-08-18

Locations

1 site across 1 country: United States