NCT02978209

Comparison of Different Concentrations of Carbamide as Moisturizers in Ichthyosis Vulgaris

Double Blinded Randomized Clinical Study of Carbamide as Moisturizer in Ichthyosis Vulgaris

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University of Aarhus · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A randomized double blinded clinical trial will be conducted comparing the effect of two simple basic moisturizers only different in the concentration of carbamide (urea). The concentrations of carbamide will be tested are 0 and 7.5, respectively. The study will be conducted as a split-body-study and will contain two arms randomized to comparing 0 and 7.5 % carbamide, respectively. Approximately 20 patients with at least clinically verified Ichthyosis Vulgaris will be enrolled to each study arm. The effect of the moisturizers will be assessed by clinical examination (score), patients assesment of effect and measurement of transepidermal water loss (TEWL) and other skin parameters.

Conditions

• Ichthyosis Vulgaris

Interventions

Type	Name	Description
DEVICE	7.5 %	Patient untreated with moisturizers for 1-2 weeks will start applying moisturizers containing urea at concentration 0 % on one half of the body twice a day while applying the same moisturizer with 7.5 % urea on the other half of the body in the same quantity at the same frequence

Timeline

• Start date: 2019-11-01
• Primary completion: 2020-01-01
• Completion: 2020-03-31
• First posted: 2016-11-30
• Last updated: 2019-11-01

Locations

1 site across 1 country: Denmark