NCT02974894

The Effects of Lactobacillus Plantarum on Cortisol, IgA and Alpha-amylase Levels in Human Saliva During Stress

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Lund University · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

In the present study the main goal has been to clarify the effect of the probiotic bacteria Lactobacillus plantarum 299v on the salivary cortisol level in young adults under examination stress. Salivary IgA from minor glands and in whole human saliva was measured as alternative marker of stress. The hypothesis was that the levels of cortisol would be reduced or stabilized in the test group in comparison to the placebo group where the cortisol levels were expected to increase due to the examination-induced stress. By contrast, the salivary IgA levels were expected to increase in the test group in comparison to the placebo group.

Conditions

• Stress Reaction

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic (Lactobacillus Plantarum)
DIETARY_SUPPLEMENT	Placebo

Timeline

• Start date: 2013-02-01
• Primary completion: 2013-03-01
• Completion: 2013-05-01
• First posted: 2016-11-29
• Last updated: 2016-12-01