NCT02971176

Low-dose Protocol for Computed Tomography-guided Lung Biopsy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 280 (actual)
• Sponsor: Xuzhou Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the diagnostic accuracy and complication rate between low-dose computed tomography-guided and standard-dose computed tomography-guided lung biopsy.

Detailed description

With the comprehensive usage of computed tomography examination, patients are more and more aware of the radiation dose of computed tomography. Concerns over the potential for radiation induced malignancies have increasingly been published in the scientific literature and reported in the popular press. The risk is highest for younger patients, who have more radiation-sensitive tissues and longer life expectancies than adults. Recently, the United States Food and Drug Administration announced an initiative to reduce unnecessary radiation exposure from medical imaging. At present, low-dose computed tomography protocol is widely used for the diagnosis of cardiovascular and cerebrovascular diseases. Computed tomography-guided lung biopsy is widely used for diagnosis of lung nodules and masses. However, it requires repeating scanning to guide the needles, which inevitably increases the radiation dose. Therefore, low-dose protocol was also used in the computed tomography-guided lung biopsy procedure. The purpose of this study is to compare the diagnostic accuracy and complication rate between low-dose computed tomography-guided and standard-dose computed tomography-guided lung biopsy.

Conditions

• Lung Cancer, Adenocarcinoma
• Lung Inflammatory Pseudotumor

Interventions

Type	Name	Description
RADIATION	Low-dose protocol computed tomography	Radiation dose under the low-dose protocol computed tomography (120 kilovolt, 15 milliampere seconds)
RADIATION	Standard-dose protocol computed tomography	Radiation dose under the standard-dose protocol computed tomography (120 kilovolt, 150 milliampere seconds)

Timeline

• Start date: 2016-11-30
• Primary completion: 2019-05-31
• Completion: 2019-05-31
• First posted: 2016-11-22
• Last updated: 2019-06-04

Locations

1 site across 1 country: China