NCT02970214

Follow-up of GANI_MED Cardio Cohorts

Greifswald Approach to Individualized Medicine (GANI_MED) - Follow-up of Cardiovascular Cohorts

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,200 (estimated)
• Sponsor: University Medicine Greifswald · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Follow-up of two hospital-based patient cohorts (heart failure, metabolic comorbidities in CVD), recruited at baseline by the GANI\_MED-project (Greifswald Approach to Individualized Medicine). Standardized protocols will be used for the assessment of medical history, laboratory biomarkers, and the collection of various biosamples for bio-banking purposes. Comparisons with the general background population will be performed.

Detailed description

5-year follow-up of two hospital-based patient cohorts (heart failure, metabolic comorbidities in CVD), recruited at baseline by the GANI\_MED-project (Greifswald Approach to Individualized Medicine). Subjects will be comprehensively phenotypes using standardized protocols for the assessment of medical history, laboratory biomarkers, and the collection of various biosamples for bio-banking purposes. A multi-omics based biomarker assessment including genome-wide genotyping, transcriptome, metabolome, and proteome analyses complements the multi-level approach of GANI\_MED. Comparisons with the general background population as characterized by the Study of Health in Pomerania (SHIP) will be performed.

Conditions

• Chronic Heart Failure
• Metabolic Syndrome

Interventions

Type	Name	Description
OTHER	no intervention, only observational	no intervention, only observational

Timeline

• Start date: 2016-11-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2016-11-21
• Last updated: 2023-12-12

Locations

1 site across 1 country: Germany