Clinical Trials Directory

Trials / Completed

CompletedNCT02967354

[11C]5-Hydroxy-tryptophan PET for Assessment of Islet Mass in Type 2 Diabetes

[11C]5-Hydroxy-tryptophan Positron Emission Tomography for Assessment of Islet Mass During Progression of Type 2 Diabetes

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
39 (actual)
Sponsor
Per-Ola Carlsson · Academic / Other
Sex
All
Age
Healthy volunteers
Accepted

Summary

Cross-sectional study to investigate subjects at different stages of type 2 diabetes development with expected stratification of pancreatic islet mass. Non-diabetic individuals were assigned as control. The primary outcome was the \[11C\]5-hydroxy-tryptophan uptake and retention in the pancreas as a surrogate marker for the endogenous islet mass.

Conditions

Interventions

TypeNameDescription
RADIATIONPositron emission tomography with the tracer [11C]5-hydroxy-tryptophanEstimation of islet mass by PET using the tracer \[11C\]5-hydroxy-tryptophan

Timeline

Start date
2013-01-01
Primary completion
2015-10-01
Completion
2015-10-01
First posted
2016-11-18
Last updated
2018-01-30
Results posted
2017-11-29

Source: ClinicalTrials.gov record NCT02967354. Inclusion in this directory is not an endorsement.