Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT02965417

Sym004 in Metastatic Colorectal Cancer and ECD-EGFR Patients

An Open-label, Multicenter, Phase 2 Trial Investigating Sym004 in Patients With Metastatic Colorectal Cancer and Acquired Resistance to Anti-EGFR Monoclonal Antibodies and Documented Mutation of Extra Cellular Domain of EGFR (ECD-EGFR)

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Symphogen A/S · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a single arm, phase 2, open-label, multicenter trial in patients with metastatic colorectal cancer (mCRC) and acquired resistance to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (mAbs) and documented mutation of extra cellular domain EGFR (ECD-EGFR).

Conditions

Interventions

TypeNameDescription
DRUGSym004Sym004 is a 1:1 mixture of two monoclonal antibodies (mAbs) which bind to two non-overlapping epitopes of the Epidermal Growth Factor Receptor (EGFR).

Timeline

Start date
2016-12-01
Primary completion
2017-01-01
Completion
2017-01-01
First posted
2016-11-16
Last updated
2017-02-01

Source: ClinicalTrials.gov record NCT02965417. Inclusion in this directory is not an endorsement.