Clinical Trials Directory

Trials / Unknown

UnknownNCT02963155

Study of Natural Killer Cells in Patients With Metastatic Prostate Cancer: Relationship With Survival and Response Time to Castration

Prospective Study of Natural Killer Cells in Patients With Metastatic Prostate Cancer: Relationship With Survival and Response Time to Castration

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Institut Paoli-Calmettes · Academic / Other
Sex
Male
Age
18 Years
Healthy volunteers
Not accepted

Summary

Prospective research of Natural Killer cells as predictive biomarkers to stratify patients likely to have longer response time to castration.

Detailed description

The main objective is to validate prospectively the results of a retrospective study showing a correlation between the level of NKp30 and NKp46 receptor-activators expression on the surface of NK cells and 1) the survival time, 2) the response time to castration in patients with metastatic prostate cancer. Prospective monocenter, open-label study. During a visit in the frame of management of the disease, a single blood sample will be collected. Patients will then have a standard care follow-up for a period of 5 years. Follow up data (death, progression) will be collected every 6 months.

Conditions

Interventions

TypeNameDescription
OTHERBlood samples

Timeline

Start date
2016-11-01
Primary completion
2018-07-07
Completion
2021-11-01
First posted
2016-11-15
Last updated
2020-01-10

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT02963155. Inclusion in this directory is not an endorsement.