NCT02960412

Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy

Randomized Controlled Trial Evaluating Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: University of South Florida · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates if administration of IV furosemide leads to expedited confirmation of ureteral patency when compared to placebo (IV saline) in routine cystoscopy performed after urogynecologic surgery.

Detailed description

Cystoscopy is performed routinely after urogynecologic surgery to ensure there was no injury to the urinary tract (urethra, bladder, or ureters). In order to confirm that no damage occurred to the ureters, a jet of urine must be visualized from each ureteral opening. The time it takes to confirm this ureteral patency is variable and some sources suggest using furosemide to decrease the time it takes to see these jets. This study will evaluate what effect, if any, this medicine has on time to confirming ureteral patency.

Conditions

• Cystoscopy

Interventions

Type	Name	Description
DRUG	furosemide	10mg lasix given intraoperatively
DRUG	Normal Saline	Normal saline given intraoperatively as placebo

Timeline

• Start date: 2017-05-01
• Primary completion: 2018-03-31
• Completion: 2018-06-30
• First posted: 2016-11-09
• Last updated: 2019-03-28

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study