NCT02960308

Whole-Neck Computed Tomography Perfusion Scan in Imaging Patients With Head and Neck Tumors

A Pilot Study of Whole-Neck CT Perfusion With the Toshiba Aquilion ONE ViSION-320 Detector Row CT Scanner for Use in Head &Amp; Neck Tumor Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 49 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This pilot clinical trial studies how well whole-neck computed tomography perfusion scans work in imaging patients with head and neck tumors. Diagnostic imaging procedures, such as whole-neck computed tomography perfusions scans, may provide more information about the blood supply to head and neck tumors which may help doctors plan better treatment.

Detailed description

PRIMARY OBJECTIVES: I. To assess the difference in whole-neck computed tomography perfusion (WNCTP) parameters (blood volume \[BV\], blood flow \[BF\], capillary permeability \[CP\] and mean transit time \[MTT\]) between head and neck tumor masses (benign or malignant) and adjacent normal skeletal muscle within the same patient. II. To assess whether the difference in WNCTP parameters between tumor masses and adjacent normal skeletal muscle is different between patients with benign tumor versus (vs.) malignant tumor. III. To assess the correlation in WNCTP parameters between tumor masses and adjacent normal skeletal muscle. IV. Determine if more suspicious cervical lymph nodes will be seen using the whole-neck coverage employed in WNCTP compared to the limited coverage of traditional neck CTP. OUTLINE: Patients undergo WNCTP scan over 2-3 minutes during standard of care computed tomography (CT). After completion of study, patients are followed up within 2 days.

Conditions

• Head and Neck Neoplasm
• Malignant Head and Neck Neoplasm

Interventions

Type	Name	Description
RADIATION	Computed Tomography Perfusion Imaging	Undergo WNCTP scan

Timeline

• Start date: 2016-10-20
• Primary completion: 2021-06-14
• Completion: 2021-06-14
• First posted: 2016-11-09
• Last updated: 2023-08-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study