Clinical Trials Directory

Trials / Completed

CompletedNCT02957682

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Praluent on Neurocognitive Function in Patients With Heterozygous Familial Hypercholesterolemia or With Non-Familial Hypercholesterolemia at High and Very High Cardiovascular Risk

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
2,176 (actual)
Sponsor
Regeneron Pharmaceuticals · Industry
Sex
All
Age
40 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to evaluate the effect on mental state (known as "neurocognitive function") with use of Praluent.

Conditions

Interventions

TypeNameDescription
DRUGPraluent (Alirocumab)
DRUGPlacebo

Timeline

Start date
2016-11-02
Primary completion
2020-03-05
Completion
2020-03-05
First posted
2016-11-08
Last updated
2021-05-07
Results posted
2021-05-07

Locations

188 sites across 9 countries: United States, Bulgaria, Chile, Estonia, Japan, Mexico, Russia, South Africa, Ukraine

Regulatory

Source: ClinicalTrials.gov record NCT02957682. Inclusion in this directory is not an endorsement.