NCT02951624

The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: Male
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.

Detailed description

Fifteen (n=15) sedentary adult overweight males will be included in the study. All participants will undergo the four interventions in a randomized cross-over design. Wash out between intervention will be minimum four days. Control (CON): Participants will be sedentary. Sedentary time will be spent sitting in a chair, restricted to sedentary behaviors (working on a computer, reading, watching TV, etc.), with a target MET below 1.5 (i.e. 1.5 times REE). Participants will only be allowed to stand or walk to go to the toilet. Breaker: Participants will be breaking up prolonged sitting with 2 min intervals of low intensity walking. Intermediate: Participants will be breaking up prolonged sitting with 6 min intervals of low intensity walking Prolonger: Participants will be breaking up prolonged sitting with 12 min intervals of low intensity walking All interventions will be matched for total physical activity as well as sitting. Thus, we aim for the active interventions to be iso-caloric.

Conditions

• Sedentary Lifestyle
• Overweight and Obesity
• Metabolic Disease

Interventions

Type	Name	Description
BEHAVIORAL	Control	Control intervention
BEHAVIORAL	Breaker	Short breaks of physical activity
BEHAVIORAL	Prolonger	longer breaks of physical activity
BEHAVIORAL	Intermediate	Intermediate breaks of physical activity

Timeline

• Start date: 2016-11-01
• Primary completion: 2018-07-15
• Completion: 2018-07-15
• First posted: 2016-11-01
• Last updated: 2018-12-14

Locations

1 site across 1 country: Denmark