Clinical Trials Directory

Trials / Completed

CompletedNCT02949830

A Study to Evaluate Long-term Safety and Clinical Activity of Givosiran (ALN-AS1) in Patient With Acute Intermittent Porphyria (AIP)

A Multicenter, Open-label Extension Study to Evaluate the Long-term Safety and Clinical Activity of Subcutaneously Administered ALN-AS1 in Patients With Acute Intermittent Porphyria Who Have Completed a Previous Clinical Study With ALN-AS1

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Alnylam Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the long-term safety, tolerability and pharmacokinetics of givosiran (ALN-AS1) in AIP patients who completed study ALN-AS1-001 (NCT02452372).

Conditions

Interventions

TypeNameDescription
DRUGGivosiranGivosiran by subcutaneous (SC) injection.

Timeline

Start date
2016-10-01
Primary completion
2021-11-05
Completion
2021-11-05
First posted
2016-10-31
Last updated
2024-03-12
Results posted
2024-03-12

Locations

5 sites across 3 countries: United States, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT02949830. Inclusion in this directory is not an endorsement.