NCT02949739

Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes

Lifestyle Intervention to Prevent Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 5,244 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The investigators' general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities from diverse settings.

Detailed description

The specific aims of the proposed iHealth-T2D study are: 1. Determine whether intensive lifestyle modification vs usual care reduces risk of T2D (primary endpoint) amongst South Asians with i. central obesity; ii. prediabetes and iii. overall (with central obesity and / or obesity). 2. Investigate secondary endpoints, including health gains in family members. Identify social, demographic and environmental factors influencing primary and secondary endpoints. 3. Carry out a health economic analysis of lifestyle modifications vs usual care for prevention of T2D on the Indian subcontinent and Europe. Quantify the cost-effectiveness of screening by waist circumference vs HbA1c.

Conditions

• Type 2 Diabetes

Interventions

Type	Name	Description
BEHAVIORAL	Intensive lifestyle modification	The intervention is delivered as 9 face-face and 13 telephone contact sessions over 12 months. Index cases are the focus for the intervention, but lifestyle modification encourages the whole family to adopt healthy living.

Timeline

• Start date: 2015-01-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2016-10-31
• Last updated: 2024-03-28

Locations

1 site across 1 country: United Kingdom