Trials / Completed
CompletedNCT02949154
Elevated LDH Serum Levels and FDG-PET in Metastatic Melanoma Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 65 (actual)
- Sponsor
- University Medical Center Groningen · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A retrospective study investigating the relationship between FDG-PET uptake and LDH levels.
Detailed description
Patient characteristics, tumour characteristics including the BRAF mutation status and baseline serum S100B and LDH levels of each patient will be retrospectively determined from the electronical patient file. In each patient, tumour burden and 18F-FDG uptake of the tumour lesions will be measured using multiple standard quantification parameters of the baseline 18F-FDG-PET scan. Tumour burden will also be measured on the baseline contrast enhanced CT scan. The correlation of each FDG-PET parameter with baseline LDH and S100B levels, respectively, will be analyzed using univariate and multivariate regression analysis.
Conditions
Timeline
- Start date
- 2016-11-01
- Primary completion
- 2017-04-01
- Completion
- 2017-04-01
- First posted
- 2016-10-31
- Last updated
- 2024-05-06
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT02949154. Inclusion in this directory is not an endorsement.