Trials / Completed
CompletedNCT02947607
Investigation of the Role of the Microbiome in the Pathogenesis of Colorectal Adenoma and Carcinoma
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 799 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is the investigation of new host-microbiome interactions promoting adenoma formation and adenocarcinoma progression. For that purpose, the investigators will collect saliva, stool and colon biopsy specimens from patients referred to colonoscopy or surgical resection of colorectal tumor. Besides, a questionnaire about diet, lifestyle and medical history will be collected. Sample analysis will involve simultaneous characterization of host and microbiota genomic and transcriptomic components.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Colon biopsies |
Timeline
- Start date
- 2016-07-01
- Primary completion
- 2018-12-01
- Completion
- 2019-04-01
- First posted
- 2016-10-28
- Last updated
- 2023-01-27
Locations
2 sites across 2 countries: Belgium, Netherlands
Source: ClinicalTrials.gov record NCT02947607. Inclusion in this directory is not an endorsement.