Clinical Trials Directory

Trials / Unknown

UnknownNCT02947191

Collagen Membrane Combined With HUC-MSCs Transplantation in Patients With Nasal Septum Perforation

The Safety and Efficacy Assessment of Collagen Membrane Combined With Human Umbilical Cord Mesenchymal Stem Cells (HUC-MSCs) Transplantation in Patients With Nasal Septum Perforation

Status
Unknown
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
12 (estimated)
Sponsor
Chinese Academy of Sciences · Other Government
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the safety and efficacy of collagen membrane combined with human clinical grade umbilical cord mesenchymal stem cells(HUC-MSCs) transplantation in patients with chronic nasal septum perforation.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCollagen membrane + HUC-MSCsAfter separating bilateral nasal septum mucosas via septum reconstruction incision under endoscopy, the clinical grade HUC-MSCs combined with collagen membrane will be transplanted between the bilateral nasal septum mucosas and fixed. The patients will be treated with antibiotics for 1 week, and with naristillae menthae compositae, mucus promoting agent and other drugs for improving microcirculation for 1 month.

Timeline

Start date
2016-11-01
Primary completion
2021-12-01
Completion
2021-12-01
First posted
2016-10-27
Last updated
2021-01-05

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT02947191. Inclusion in this directory is not an endorsement.