Clinical Trials Directory

Trials / Terminated

TerminatedNCT02945046

A Study to Evaluate the Efficacy and Safety of TEV-48125 (Fremanezumab) for the Prevention of Episodic Cluster Headache (ECH)

A Multicenter, Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of 2 Dose Regimens (Intravenous/Subcutaneous and Subcutaneous) of TEV-48125 Versus Placebo for the Prevention of Epidosic Cluster Headache

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
169 (actual)
Sponsor
Teva Branded Pharmaceutical Products R&D, Inc. · Industry
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This is a 13-week, multicenter, randomized, double-blind, double-dummy, placebo-controlled, parallel-group study to compare the efficacy and safety of 2 dose regimens of TEV-48125 (Fremanezumab) versus placebo in adult participants for the prevention of ECH.

Conditions

Interventions

TypeNameDescription
DRUGFremanezumabFremanezumab will be administered per dose and schedule specified in the arm.
DRUGPlaceboPlacebo matching to fremanezumab will be administered per schedule specified in the arm.

Timeline

Start date
2017-01-19
Primary completion
2019-05-13
Completion
2019-05-13
First posted
2016-10-26
Last updated
2021-11-09
Results posted
2020-04-13

Locations

82 sites across 12 countries: United States, Australia, Canada, Finland, Germany, Israel, Italy, Netherlands, Poland, Spain, Sweden, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT02945046. Inclusion in this directory is not an endorsement.