NCT02942251

Relapse Predicting Model for First Episode Depression

The Study of Relapse Predicting Model for First Episode Depression: Big Data Analysis Based on Clinical Features and Immunochemistry

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Shanghai Mental Health Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Major depressive depression(MDD) is an severe public mental disorders. The purpose of current study is using big data analysis based on clinical features and immunochemistry to investigate and establish an relapse predict model for patients with first episode MDD.

Detailed description

Major depressive depression(MDD) is an severe public mental disorders. The purpose of current study is using big data analysis based on clinical features and immunochemistry to investigate and establish an relapse predict model for patients with first episode MDD. This study includes two steps. Step 1: Big data analysis based on the clinical features and immunochemical figures of 30000 patients with first episode MDD will be conducted to construct a relapse predict model. Step 2: 300 patients with first episode MDD will be recruited in this step. Physicians prefer to give corresponding treatment recommendation based on the predictive factors to verify this relapse model.

Conditions

• Major Depressive Disorders

Interventions

Type	Name	Description
OTHER	Clinical features and medication	This group will be suggested to take optimize treatment according to Chinese treatment guidelines.
OTHER	Psycho-social	This group will be suggested to add on psychotherapy on medical treatment.
OTHER	immunology	This group will be suggested to add on Omega-3 polyunsaturated fatty acid(PUFAs) on medical treatment.
OTHER	Laboratory abnormality	This group will be suggested to more safety antidepressants.
OTHER	Comorbidity	This group will be suggested to treat their comorbidities as well as treat MDD.
OTHER	Treatment as usual	Patients will accept routine treatments based on psychiatrist experience, not based on the relapse predict model.

Timeline

• Start date: 2016-12-01
• Primary completion: 2018-12-01
• Completion: 2019-12-01
• First posted: 2016-10-24
• Last updated: 2016-10-26