NCT02934009

Dermal Profile Analysis Using the NMR-MOUSE

Dermal Profile Analysis Using NMR-MOUSE (Nuclear Magnetic Resonance - Mobile Universal Surface Explorer)

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: RWTH Aachen University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The determination of fluid status in dialysis patients is a major clinical problem. In this study the NMR-MOUSE is used to determine if it can be used to non-invasively determine hydration status of the skin. This evaluation will be performed in dialysis patients and healthy volunteers.

Detailed description

Excretion of urine is impaired in terminal chronic kidney disease patients often requiring dialysis. Fluid management of dialysis patients is solely based on body weight differences before and after dialysis. Patients can suffer from either hypotension if too much fluid is eliminated by dialysis or from fluid-overload symptom (e.g. shortness of breath, edema) if not enough fluid is eliminated. In this study a mobile non-invasive NMR-MOUSE setup (a nuclear magnetic resonance spectroscopy measurement) is used to measure the hydration status of the skin.

Conditions

• Exposure to Magnetic Field
• Hypotension During Dialysis
• Disturbance; Balance, Fluid

Interventions

Type	Name	Description
DEVICE	Dermal nuclear magnetic resonance (NMR)-profile measurement	Nuclear magnetic resonance (NMR)-profile measurement of the dermis

Timeline

• Start date: 2016-10-01
• Primary completion: 2020-05-08
• Completion: 2020-05-08
• First posted: 2016-10-14
• Last updated: 2021-03-24

Locations

1 site across 1 country: Germany