NCT02931162

The Effects of Moxibustion on Ulcerative Colitis

Efficacy of Moxibustion Treatment on Patients With Ulcerative Colitis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Shanghai Institute of Acupuncture, Moxibustion and Meridian · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To investigate the mechanism and effects of moxibustion on patients with ulcerative colitis.

Detailed description

A total of 60 patients with UC were randomly divided into the following 2 groups: a) Herb-partition moxibustion (Treatment Group) and b) Sham herb-partition moxibustion (Control Group). All patients in the trial will be treated with moxibustion 3 times a week, once a day for 30 minutes, for a total of 12 weeks. MRI will be used to observe the changes on brain structure and function in patients with UC, and further research on the characteristics of the brain nerve response of these patients with herb-partition moxibustion. In addition, tissue morphology and molecular biology tests will be conducted to observe the regulation and expression of VDR and antimicrobial peptides in the intestinal mucosa of UC patients. All these steps will be done in order to provide experimental basis for the mechanism of the effects of herb-partition moxibustion in the treatment of UC.

Conditions

• Ulcerative Colitis

Interventions

Type	Name	Description
OTHER	Herb-partitioned moxibustion	Patients receive herb-partition moxibustion 3 times a week, once a day for 30 minutes, for a total of 12 weeks.
OTHER	Sham herb-partitioned moxibustion	Patients receive sham herb-partition moxibustion 3 times a week, once a day for 30 minutes, for a total of 12 weeks.

Timeline

• Start date: 2016-08-23
• Primary completion: 2018-12-31
• Completion: 2019-12-31
• First posted: 2016-10-12
• Last updated: 2021-03-18

Locations

1 site across 1 country: China