NCT02927600

Bed and Breakfast (B&B) Study

Impact of Low Glycemic Responses Breakfast or Dinner on Postprandial Glycemia of the Subsequent Meals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 50 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The primary objective is to determine which among high vs low Glycemic Index (GI) / Glycemic Responses (GR) interventions at breakfast or at dinner is the most effective for lowering glycemic response of the subsequent standard meal.

Detailed description

Consumption of low Glycemic Index (GI) foods has been shown to not only attenuate blood glucose response during the postprandial period immediately following a meal but to have also positive metabolic effects at the subsequent meal, known as the "second-meal effect" by reducing glucose excursion beyond actual meal. The relative importance of the timing of the glycemic load variation (e.g., breakfast or dinner) on the overall, 24h, glycemic control has not been investigated in detail. We hypothesize that eating low GI foods in a single meal either for breakfast or for dinner would have different consequential effects on glycemic control over the following meal and thereafter during 24 hours. In order to establish the relative importance of breakfast or dinner in predicting glycemic control/response of the following meal and for a 24-hour period this study will use comprehensive methods including Continuous Glucose Monitoring Systems (CGMS) as well as measuring postprandial blood glucose and insulin.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Low GI Breakfast	Intake of low GI breakfast
OTHER	High GI Breakfast	Intake of high GI breakfast
OTHER	Low GI Dinner	Intake of Low GI dinner
OTHER	High GI Dinner	Intake of high GI dinner

Timeline

• Start date: 2016-09-01
• Primary completion: 2017-10-01
• Completion: 2017-10-01
• First posted: 2016-10-07
• Last updated: 2017-11-13

Locations

1 site across 1 country: Singapore