NCT02925767

Efficacy of 311-nm Ti:Sapphire Laser Versus 308-nm Excimer Laser Treatment in Vitiligo

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (estimated)
• Sponsor: The Catholic University of Korea · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

A randomized controlled non-inferiority trial based on split-body was planned to compare the efficacy of 308-nm excimer laser and 311-nm Ti:Sapphire laser in patients with vitiligo.

Detailed description

The 308-nm excimer laser (EL) has been widely used for localized vitiligo. Recently, the 311-nm Ti:Sapphire laser (TSL) was developed to treat patients with vitiligo. To compare the efficacy of TSL vs. EL in the treatment of vitiligo. A randomized controlled non-inferiority trial based on split-body was planned. The paired symmetric vitiliginous lesions will be randomized to either TSL or EL treatment groups. All lesions will be treated twice weekly for a total of 12-week period. The degree of repigmentation will be assessed as % from baseline by using a computer program every 4 weeks, and the non-inferiority margin was set at 10%. Overall 16 patients will be enrolled.

Conditions

• Vitiligo

Interventions

Type	Name	Description
DEVICE	311-nm Ti:Sapphire laser	Pallas, LaserOptek, South Korea
DEVICE	308-nm excimer laser	XTRAC, PhotoMedex, US

Timeline

• Start date: 2016-08-01
• Primary completion: 2018-01-30
• Completion: 2018-08-30
• First posted: 2016-10-06
• Last updated: 2018-01-19

Locations

1 site across 1 country: South Korea