NCT02923895

To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)

A Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 197 (actual)
• Sponsor: GlaxoSmithKline · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This single centre study will be used to investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving dentinal hypersensitivity (DH) after short term use compared with a standard fluoride dentifrice.

Detailed description

This will be a single centre, three day, randomised, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), controlled study, in participants with at least two sensitive teeth that meet all the criteria at the screening and baseline (pre-treatment) visits. DH will be assessed at baseline (pre-treatment), post-treatment and after 3 days twice daily use.

Conditions

• Dentin Sensitivity

Interventions

Type	Name	Description
OTHER	Stannous fluoride	0.454% weight by weight (w/w) stannous fluoride containing 1100 parts per million (ppm) fluoride
OTHER	Sodium monofluorophosphate	0.76% w/w sodium monofluorophosphate containing 1000 ppm fluoride

Timeline

• Start date: 2016-10-11
• Primary completion: 2016-12-16
• Completion: 2016-12-16
• First posted: 2016-10-05
• Last updated: 2018-10-29
• Results posted: 2018-10-29

Locations

1 site across 1 country: Canada