NCT02923752

Whole Brain Vessel Wall Imaging in Stroke Patients (WISP): An International Multi-Center Registry

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Cedars-Sinai Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a new vessel wall imaging-based stroke registry which will investigate the clinical utility of the whole-brain intracranial vessel wall Magnetic Resonance Imaging (MRI) technique in assessing the etiologies in patients with ischemic stroke.

Detailed description

The registry will focus on investigating the utility of whole-brain vessel wall MRI techniques in assessing the etiologies in patients with recent ischemic stroke. Patients who have had ischemic stroke (as confirmed by diffusion weighted MRI) and have had or will undergo 3D whole-brain vessel wall MRI within 8 weeks of symptom onset will be recruited into this study. It is anticipated that a total of 1000 subjects will be recruited from Feb 2017 to Feb 2019. Approximately 12 centers in the US and China will participate in the registry. MRI whole-brain vessel wall images will be analyzed for detection and characteristics of various vessel wall pathologies and association between vessel wall imaging findings and patient's clinical information.

Conditions

• Ischemic Stroke

Interventions

Type	Name	Description
DEVICE	MRI	Contrast-enhanced MRI

Timeline

• Start date: 2017-02-01
• Primary completion: 2019-08-01
• Completion: 2019-08-01
• First posted: 2016-10-05
• Last updated: 2018-08-14

Locations

12 sites across 2 countries: United States, China

Regulatory

• FDA-regulated device study