Clinical Trials Directory

Trials / Terminated

TerminatedNCT02923531

Addition of X4P-001 to Nivolumab Treatment in Participants With Renal Cell Carcinoma

A Phase 1B/2A Trial Adding X4P-001 in Patients Receiving Nivolumab for Treatment of Advanced Clear Cell Renal Cell Carcinoma

Status
Terminated
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
9 (actual)
Sponsor
X4 Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if the combination of X4P-001 plus nivolumab is safe and tolerable. Secondly, the study will investigate if adding X4P-001 to nivolumab treatment has an effect on the body and the cancer tumor, in participants receiving nivolumab but not exhibiting a radiological response.

Conditions

Interventions

TypeNameDescription
DRUGX4P-001X4P-001 will be administered as per the dose and schedule specified in the arm.
DRUGNivolumabNivolumab will be administered as per the dose and schedule specified in the arm.

Timeline

Start date
2016-12-07
Primary completion
2018-08-08
Completion
2018-08-08
First posted
2016-10-04
Last updated
2022-12-29
Results posted
2022-12-29

Locations

4 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT02923531. Inclusion in this directory is not an endorsement.