Clinical Trials Directory

Trials / Completed

CompletedNCT02923258

Postoperative CCRT With Docetaxel vs Cisplatin in High Risk Oral Cavity Cancer

Postoperative Radiation and Concurrent Chemotherapy With Weekly Docetaxel Versus Cisplatin in Patients With High-risk Oral Cavity Cancer: a Randomized Phase II Clinical Trial

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
224 (actual)
Sponsor
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This is a randomized,controled, phase II, open label study of postoperative concurrent chemoradiotherapy with Docetaxel versus Cisplatin for high-risk squamous cell carcinoma of the oral cavity cancer.The primary purpose of this study is to evaluate the efficacy of concurrent chemoradiotherapy with docetaxel in OCC patients.

Conditions

Interventions

TypeNameDescription
DRUGDocetaxel20mg/m2/w
DRUGCisplatin100mg/m2/q3w
RADIATIONIMRTa total dose of 60Gy in 30fractions over 6 weeks

Timeline

Start date
2018-04-21
Primary completion
2022-02-28
Completion
2023-04-30
First posted
2016-10-04
Last updated
2024-06-20

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT02923258. Inclusion in this directory is not an endorsement.