Trials / Completed
CompletedNCT02922491
Effect of Vitamin E Supplementation in Methylation and microRNAs Profile
EFFECT OF VITAMIN E SUPPLEMENTATION IN METHYLATION AND MICRORNAS PROFILE IN ADULT WOMEN WITH OVERWEIGHT
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 55 (actual)
- Sponsor
- Federal University of Paraíba · Academic / Other
- Sex
- Female
- Age
- 20 Years – 59 Years
- Healthy volunteers
- Accepted
Summary
It is a study of clinical and interventional character, in which individuals who participate in the intervention will be selected for convenience of the project database entitled "Second Cycle Diagnosis and Intervention Food Situation, Nutrition and Noncommunicable Disease More Prevalent Population of the city of João Pessoa / PB ". They will be invited to participate in the intervention female subjects, overweight or obese, aged 20 and 59 years. The selected individuals will be distributed randomly into four groups: receive daily supplementation of 01 capsules containing 400 mg of vitamin E synthetic source (Group 1); receive daily supplementation of 01 capsules containing 400 mg of natural source vitamin E (Group 2); receive daily supplementation of 01 placebo capsule (control group); and non-intervention group. Individuals of intervention groups will receive dietary plan respecting individual needs, in order to control weight during the 08 weeks period. The subjects of the group without intervention, did not follow a diet plan, nor did they take vitamin E or placebo capsules, and were asked to continue their current eating habits over the 8-week period This project aims to evaluate whether vitamin E supplementation may modify the methylation and microRNAs profile.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | vitamin E | daily intake of vitamin E |
| DIETARY_SUPPLEMENT | starch | daily intake of starch (control) |
Timeline
- Start date
- 2016-06-01
- Primary completion
- 2016-11-01
- Completion
- 2016-12-10
- First posted
- 2016-10-04
- Last updated
- 2018-03-23
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT02922491. Inclusion in this directory is not an endorsement.