Trials / Unknown
UnknownNCT02920203
Genetic Autopsy and Sudden Death
Genetic Autopsy and Sudden Death of Young Subject
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Academic / Other
- Sex
- All
- Age
- 2 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to better identify hereditary cardiac causes of sudden unexpected death in young subjects through Next-Generation Sequencing of autopsy tissue
Detailed description
Monitoring : For index cases group, all the data will be monitored. For the relatives group, only the informed consent will be monitored Statistical analysis : * Evaluate the additional elucidation rate of unexpected sudden death * Evaluate causes obtained by Next Generation Sequencing (NGS) ( in comparison with conventional autopsy (macroscopic and / or microscopic) * Descriptive study of the causes of sudden unexpected death, identified hereditary cardiac causes percentages compared via various diagnostic approaches * Cost-effectiveness analysis Data Management : A database is created for the AGEMOS study with control of the discrepancies. All the index cases' data entered in the data base will be double checked
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Heart and spleen tissue | genetic sequencing |
Timeline
- Start date
- 2017-10-11
- Primary completion
- 2020-09-01
- Completion
- 2020-12-01
- First posted
- 2016-09-30
- Last updated
- 2017-11-06
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT02920203. Inclusion in this directory is not an endorsement.