NCT02917707

Integrative Analysis of CRC Liver Metastasis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Da Fu · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The investigators will perform integrative analysis of CRC liver metastasis

Detailed description

The investigators will analyzed proteomes of paired normal colorectal tissues and colorectal cancer (CRC) with or without liver metastasis, sequenced transcriptomes, performed whole exome sequencing, and single nucleotide polymorphism (SNP) array profiling for triplets, each comprising normal colorectal tissue, primary colorectal carcinoma, and its synchronous matched liver metastasis, as well as analyzed genomics of CRC characterized previously by The Cancer Genome Atlas (TCGA) to conduct integrated proteogenomic analyses.

Conditions

• Metastasis

Interventions

Type	Name	Description
OTHER	normal colorectal tissues	The investigators will extract total protein, DNA and RNA from these groups.

Timeline

• Start date: 2016-01-01
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2016-09-28
• Last updated: 2016-09-28

Locations

2 sites across 1 country: China