NCT02917070

Parental Consanguinity and Family History of Kidney Disease in Turkish Kidney Disease Population

The Importance of Parental Consanguinity and Family History of Kidney Disease in Turkish Adult Chronic Kidney Disease Population

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,576 (actual)
• Sponsor: Istanbul University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Inbreeding and consanguineous marriages are known to increase the risk of autosomal recessive disorders. The aim of this study was to examine the association between consanguinity and kidney diseases in the adult Turkish population.

Detailed description

This was a national, cross-sectional study recruiting patients from nephrology out-patient clinics and dialysis units. All patients between 18 and 70 years of age who were on follow up in outpatient clinic and dialysis unit at the Istanbul Medical Faculty from October 2009 to October 2015 were included in the study. All patients and healthy controls enrolled in this study gave informed consent to participate in the survey. They were all asked to answer a questionnaire including socio-demographic data, history of familial kidney disease and consanguineous marriage. Additional information was obtained from their private physicians and medical files. To ensure reliability of administration of the questionnaire, all interviewers underwent training using a standardized protocol.

Conditions

• Hereditary Diseases

Interventions

Type	Name	Description
OTHER	Patients	In this study we aimed to investigate effect of family history and consanguineous marriage in the development of CKD in the adult Turkish population.

Timeline

• Start date: 2016-02-01
• Primary completion: 2016-05-01
• Completion: 2016-08-01
• First posted: 2016-09-28
• Last updated: 2016-09-28

Locations

1 site across 1 country: Turkey (Türkiye)