NCT02914912

Investigation of Chronic Intestinal Ischemia

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Patients suspected of chronic mesenteric ischemia caused by atherosclerosis or median arcuate ligament syndrome shall be investigated with trans mucosal and transserosal laser Doppler flowmeter and visible light spectroscopy.

Detailed description

Patients with suspected chronic mesenteric ischemia (included median arcuate ligament syndrome/truncus coeliacus compression syndrome) referred to the vascular surgery department for investigation of splanchnic and mesenteric circulation shall be included in this study. In addition to CT angiography, patients shall be investigated 1. with gastroscopy-assisted laser Doppler flowmetry and light spectroscopy (GALS) before and after the surgical or endovascular treatment 2. Endoscopic ultrasound before and after the surgical or endovascular treatment 3. Transserosal laser Doppler flowmetry and light spectroscopy during the surgical treatment 4. Plasma Ischemia bio-markers, before and after the surgical or endovascular treatment 5. Health related quality of life assessed with EQ5D and SF36 before and after the treatment 6. clinical outcomes of the treatment (early and late results).

Conditions

• Chronic Mesenteric Ischemia

Timeline

• Start date: 2016-09-01
• Primary completion: 2025-01-01
• Completion: 2025-01-01
• First posted: 2016-09-26
• Last updated: 2024-08-06

Locations

2 sites across 1 country: Norway