NCT02913781

Polar Body Removal Before ICSI for Oocyte Activation in Previous Fertilization Failure Cases

Polar Body Removal Before ICSI as a Method of Oocyte Activation in Previous Fertilization Failure Cases

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Benha University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Cases which undergone ICSI before with failure of fertilization will do another ICSI cycle with removal of the polar body just before the ICSI procedure and sperm injection at the site of polar body removal. This study group will be evaluated with another group with the classic ICSI procedure

Detailed description

Patients with previous fertilization failure will be divided into 2 groups: Group 1 (control): Will undergo classic ICSI procedure in half the MII oocyte of the same case. Group 2 (study group): The other half of the MII oocyte of the same case will undergo: 1. Polar body removal. 2. ICSI procedure with injection of the spermatozoon in the same zona opening (done by laser for polar body removal). Results: Will be collected with evaluation of number of 2PN zygotes, Day 1, Day 2, Day 3, Day 5 embryos in all the cases.

Conditions

• Fertilization

Interventions

Type	Name	Description
PROCEDURE	polar body removal using zona drilling by laser then suction by injecting pipette	zona drilling with laser followed by polar body removal then ICSI procedure
PROCEDURE	Classic ICSI	Classic ICSI case was done be injecting sperm inside Oocyte while polar body is already existed at 6 or 12 O'clock position.

Timeline

• Start date: 2016-02-01
• Primary completion: 2017-12-01
• Completion: 2018-01-01
• First posted: 2016-09-26
• Last updated: 2018-09-11

Locations

1 site across 1 country: Egypt