NCT02910206

Etomidate to Improve Outcome in Elderly Patients

Comparative Effect of Etomidate and Propofol on Major Complications After Abdominal Surgery in Elderly Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,917 (actual)
• Sponsor: Zhihong LU · Academic / Other
• Sex: All
• Age: 65 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Elderly patients have high mortality and postoperative complications rate after surgery, especially postoperative cardiac complications. A meta-analysis revealed haemodynamic intraoperative events significantly increased the risk of postoperative cardiac complications.To limit the risk, optimize the intraoperative management of circulation is essential. Anesthetic drug may effect on the haemodynamic intraoperative, reduction of postoperative complications should aimed at choosing the optimal anesthetic drug with minimal effect on haemodynamic.So this study is to explore the comparative efficacy and safety of anesthetic drug (etomidate or propofol) in elderly patients

Conditions

• Postoperative Complications

Interventions

Type	Name	Description
DRUG	Etomidate	etomidate is given intravenously
DRUG	propofol	propofol is given intravenously
DRUG	Sufentanil	sufentanil is given intravenously
DRUG	Cisatracurium	Cisatracurium is given intravenously

Timeline

• Start date: 2017-08-15
• Primary completion: 2019-11-20
• Completion: 2020-11-20
• First posted: 2016-09-21
• Last updated: 2020-12-10

Locations

1 site across 1 country: China