Trials / Unknown
UnknownNCT02908009
A Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery
An Observational Case Control Study to Identify the Role of Epigenetic Regulation of Genes Responsible for Energy Metabolism and Mitochondrial Function in the Obesity Paradox in Cardiac Surgery
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 80 (estimated)
- Sponsor
- University of Leicester · Academic / Other
- Sex
- All
- Age
- 16 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective, single-centre case control comparison of expression of target genes responsible for energy utilisation, mitochondrial function and oxidative stress and levels of histone acetylation/ DNA methylation in obese and non-obese adult cardiac surgery patients. The study aims to test several inter-related hypotheses in a consecutive sequence of patients undergoing coronary artery bypass grafting.
Conditions
Timeline
- Start date
- 2016-09-09
- Primary completion
- 2024-10-07
- Completion
- 2024-10-07
- First posted
- 2016-09-20
- Last updated
- 2023-11-14
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT02908009. Inclusion in this directory is not an endorsement.