NCT02906566

Retinol on Human Skin Aging in East Asian Descent

Discovery of Effects of Retinol on Human Skin Aging in Individuals of East Asian Descent

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: Female
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

There has been increasing evidence for different rates of natural aging in humans and one of the best organs to study human aging is skin. Studies have demonstrated anti-aging effects of topical agents (such as creams, gels, lotions, or ointments) and one of them, retinol or vitamin A, was shown to decrease fine wrinkling in skin of older individuals. Additionally, studies of retinol in humans have largely occurred in white populations and so this study aims to focus on skin aging in individuals of East Asian descent as they represent a majority of the world population. This study aims to better characterize the molecular basis of rejuvenation effects and to potentially discover new topical agents with similar and/or more effective preservation of skin youthfulness.

Conditions

• Intrinsic Aging of Skin

Interventions

Type	Name	Description
DRUG	Retinol	Retinol in the form of vitamin A lotion
DRUG	Placebo	Placebo of Retinol

Timeline

• Start date: 2015-11-01
• Primary completion: 2018-03-09
• Completion: 2018-03-09
• First posted: 2016-09-20
• Last updated: 2019-04-16
• Results posted: 2019-04-16

Locations

1 site across 1 country: United States