Trials / Completed
CompletedNCT02902380
The Effect of Dexmedetomidine on Neuroendocrine Stress Hormone Release and Heart Rate Variability in Patients Undergoing Major Spinal Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 52 (actual)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- All
- Age
- 20 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
Surgical stress induces stress hormone release and sympathetic hyperactivation. Dexmedetomidine has sympatholytic effect and attenuates stress responses. This study investigate the effect of dexmedetomidine on stress responses and autonomic nervous system balance in patients undergoing major spine surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | dexmedetomidine group | dexmedetomidine infusion (0.4 mcg/kg/h) from immediately after anesthetic induction to end of surgery |
| DRUG | control group | 0.9% saline infusion |
Timeline
- Start date
- 2016-09-27
- Primary completion
- 2017-07-01
- Completion
- 2017-07-01
- First posted
- 2016-09-15
- Last updated
- 2018-02-28
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT02902380. Inclusion in this directory is not an endorsement.