Trials / Completed
CompletedNCT02902224
Glucose and Fructose Stimulated Brain Activity in Obese Subjects Before and After Bariatric Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- University Hospital, Basel, Switzerland · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The objective is to investigate neuro-anatomical correlates of the regulation of energy intake by means of functional MRI before and after bariatric surgery. Administration of glucose as well as fructose is followed by functional brain MRI, and findings are correlated with serum glucagon-like peptide 1 (GLP-1) levels as an endogenous satiety signal in obese humans.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Tap water | 300ml tap water via nasogastric tube |
| DIETARY_SUPPLEMENT | Glucose | 300ml tap water with 75g glucose via nasogastric tube |
| DIETARY_SUPPLEMENT | Fructose | 300ml tap water with 25g fructose via nasogastric tube |
Timeline
- Start date
- 2014-04-01
- Primary completion
- 2016-08-01
- Completion
- 2016-08-01
- First posted
- 2016-09-15
- Last updated
- 2016-09-15
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT02902224. Inclusion in this directory is not an endorsement.