NCT02898441

Early Stage Lung Cancer Screening With Low-dose Computed Tomographic

Community-based Early Stage Lung Cancer Screening With Low-dose Computed Tomography in China

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 6,000 (estimated)
• Sponsor: Shanghai Chest Hospital · Academic / Other
• Sex: All
• Age: 45 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The present study is a randomized controlled trial of LDCT screening for lung cancer versus usual care. 6000 high-risk subjects (age 45-70) were recruited and randomized to the Active arm (Baseline + 2 biennial repeated LDCT screening) or to the Passive arm, followed up in usual care (Baseline + 2 biennial repeated questionnaire inquiries). Follow-up for lung cancer incidence, lung cancer mortality and overall mortality was performed. Blood samples were stored from the Active arm in a Biobank. Management of positive screening test was carried out by a pre-specified protocol.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
DEVICE	Low Dose Computed Tomography	LDCT were performed in screening arm. The abnormal nodules were defined as noncalcified nodules (NCN) larger than 4 mm.

Timeline

• Start date: 2014-01-01
• Primary completion: 2016-12-01
• Completion: 2018-12-01
• First posted: 2016-09-13
• Last updated: 2016-09-13

Locations

1 site across 1 country: China