NCT02897570

Metabolic and Neurofunctional Responses to Breakfasts

Effect of Glucose Versus Mixed Breakfast on Metabolic and Neurofunctional Responses in Healthy Individuals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Ospedale San Donato · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

This study aims at assessing the effects of glucose and different types of breakfast on metabolic and neurofunctional responses in healthy individuals. Twelve healthy subjects, on a stable diet, in a randomized-crossover fashion, received either a 50 g glucose load (control) or one of these breakfast: B1: milk (125ml) and cereals (30g); B2: milk (220ml), apple (200g) and cream chocolate filled sponge cake (30g); B3: milk (125ml), bread (50g), apple (150g) and hazelnut cream chocolate (15g). Prior and upon completion of each tolerance test, an EEG was performed to measure frontal P300-evoked potentials.

Conditions

• Feeding Behaviors
• Lack of Satiety
• Attention Deficit and Disruptive Behavior Disorders

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Glucose	50g of glucose dissolved in 250 to 300ml of water was drunk. Prior and upon completion of each glucose tolerance test, an EEG was performed.
DIETARY_SUPPLEMENT	Milk & Cereals	A breakfast (B1) including a glass of milk (125ml) and 30 g-corn flakes was consumed. Prior and upon completion of each tolerance test, an EEG was performed
DIETARY_SUPPLEMENT	Milk, apple & snack	A breakfast (B2) including a glass of milk (220ml), an apple (200g), a cream chocolate filled sponge cake (30g) was consumed. Prior and upon completion of each meal tolerance test, an EEG was performed.
DIETARY_SUPPLEMENT	Milk, apple & bread w/ cream	A breakfast (B3) including a glass of milk (125ml), an apple (150g), bread (50g, hazelnut chocolate cream (15g) was consumed. Prior and upon completion of each meal tolerance test, an EEG was performed.
DEVICE	EEG_pre	Electroencephalography (EEG) was performed prior each tolerance test to assess frontal P300-evoked potentials
DEVICE	EEG_post	Electroencephalography (EEG) was performed upon completion of each tolerance test to assess frontal P300-evoked potentials

Timeline

• Start date: 2013-10-01
• Primary completion: 2014-12-01
• Completion: 2014-12-01
• First posted: 2016-09-13
• Last updated: 2016-09-14

Locations

1 site across 1 country: Italy